Review



cytokeratin 14 ck 14  (Proteintech)


Bioz Verified Symbol Proteintech is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 97
      Buy from Supplier

    Structured Review

    Proteintech cytokeratin 14 ck 14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Cytokeratin 14 Ck 14, supplied by Proteintech, used in various techniques. Bioz Stars score: 97/100, based on 163 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cytokeratin 14 ck 14/product/Proteintech
    Average 97 stars, based on 163 article reviews
    cytokeratin 14 ck 14 - by Bioz Stars, 2026-03
    97/100 stars

    Images

    1) Product Images from "Insulin-Regulated Actin Dynamics is Disrupted in a Human Keratinocyte Model of Hailey Hailey Disease"

    Article Title: Insulin-Regulated Actin Dynamics is Disrupted in a Human Keratinocyte Model of Hailey Hailey Disease

    Journal: bioRxiv

    doi: 10.64898/2025.12.15.694174

    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) CK-14 immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Figure Legend Snippet: Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) CK-14 immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.

    Techniques Used: Immunofluorescence, Control, Staining, Expressing, Labeling, Mutagenesis, Transmission Assay, Membrane



    Similar Products

    cytokeratin 14 ck 14  (Proteintech)
    97
    Proteintech cytokeratin 14 ck 14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Cytokeratin 14 Ck 14, supplied by Proteintech, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cytokeratin 14 ck 14/product/Proteintech
    Average 97 stars, based on 1 article reviews
    cytokeratin 14 ck 14 - by Bioz Stars, 2026-03
    97/100 stars
    		  Buy from Supplier
    cytokeratin (ck)14 mouse-monoclonal antibody  (Santa Cruz Biotechnology)
    90
    Santa Cruz Biotechnology cytokeratin (ck)14 mouse-monoclonal antibody
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Cytokeratin (Ck)14 Mouse Monoclonal Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cytokeratin (ck)14 mouse-monoclonal antibody/product/Santa Cruz Biotechnology
    Average 90 stars, based on 1 article reviews
    cytokeratin (ck)14 mouse-monoclonal antibody - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ck 14 antibody  (Proteintech)
    97
    Proteintech ck 14 antibody
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Ck 14 Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ck 14 antibody/product/Proteintech
    Average 97 stars, based on 1 article reviews
    ck 14 antibody - by Bioz Stars, 2026-03
    97/100 stars
    		  Buy from Supplier
    ck 14  (Proteintech)
    97
    Proteintech ck 14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Ck 14, supplied by Proteintech, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ck 14/product/Proteintech
    Average 97 stars, based on 1 article reviews
    ck 14 - by Bioz Stars, 2026-03
    97/100 stars
    		  Buy from Supplier
    rabbit cytokeratin 14 antibody ck 14  (Danaher Inc)
    86
    Danaher Inc rabbit cytokeratin 14 antibody ck 14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Rabbit Cytokeratin 14 Antibody Ck 14, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit cytokeratin 14 antibody ck 14/product/Danaher Inc
    Average 86 stars, based on 1 article reviews
    rabbit cytokeratin 14 antibody ck 14 - by Bioz Stars, 2026-03
    86/100 stars
    		  Buy from Supplier
    anti ck 14  (Santa Cruz Biotechnology)
    94
    Santa Cruz Biotechnology anti ck 14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Anti Ck 14, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti ck 14/product/Santa Cruz Biotechnology
    Average 94 stars, based on 1 article reviews
    anti ck 14 - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    mouse monoclonal antibodies against human cytokeratin (ck) 14  (Millipore)
    90
    Millipore mouse monoclonal antibodies against human cytokeratin (ck) 14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Mouse Monoclonal Antibodies Against Human Cytokeratin (Ck) 14, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse monoclonal antibodies against human cytokeratin (ck) 14/product/Millipore
    Average 90 stars, based on 1 article reviews
    mouse monoclonal antibodies against human cytokeratin (ck) 14 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    antibodies against ck-14  (Novocastra)
    90
    Novocastra antibodies against ck-14
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Antibodies Against Ck 14, supplied by Novocastra, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/antibodies against ck-14/product/Novocastra
    Average 90 stars, based on 1 article reviews
    antibodies against ck-14 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ck 14 sc 53253 antibody  (Santa Cruz Biotechnology)
    94
    Santa Cruz Biotechnology ck 14 sc 53253 antibody
    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) <t>CK-14</t> immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.
    Ck 14 Sc 53253 Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ck 14 sc 53253 antibody/product/Santa Cruz Biotechnology
    Average 94 stars, based on 1 article reviews
    ck 14 sc 53253 antibody - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) CK-14 immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.

    Journal: bioRxiv

    Article Title: Insulin-Regulated Actin Dynamics is Disrupted in a Human Keratinocyte Model of Hailey Hailey Disease

    doi: 10.64898/2025.12.15.694174

    Figure Lengend Snippet: Representative immunofluorescence images of (a) Dsg-1 showing strong peripheral localization in control keratinocytes, but markedly reduced or absent staining in SPCA1 -/- and SPCA1 +/− cells. Magnification, 20x. Scale bar = 20 μm; (b) E-cadherin immunofluorescence showing robust expression at cell junctions in control keratinocytes but near absence in SPCA1 mutants. Magnification, 20x. Scale bar = 20 μm; (c) CK-14 immunofluorescence revealing prominent perinuclear keratin bundles in SPCA1 −/− keratinocytes, with fewer aggregates in SPCA1 +/- cells. Magnification, 40x. Scale bar = 10 μm; and (d) F-actin labeled with fluorescent phalloidin demonstrates abnormal peripheral actin accumulation and cytoplasmic actin-rich structures in SPCA1 mutant cells. Magnification, 40x. Scale bar = 10 μm. (e) Transmission electron micrographs showing intercellular gaps (black arrows), membrane blebs (asterisks) and keratin bundles (red arrowheads) in SPCA1 mutant cells compared to intact junctions (white arrows) in hTERT control. N, nucleus. Scale bar = 2 μm.

    Article Snippet: Primary antibodies against ATP2C1, GM130, Cytokeratin 14 (CK-14) (Proteintech #60320) and E-cad were incubated overnight at 4°C or at least 1 h at RT in the blocking buffer at 1:50, 1:300, 1:100 and 1:100 dilution, respectively.

    Techniques: Immunofluorescence, Control, Staining, Expressing, Labeling, Mutagenesis, Transmission Assay, Membrane